On Phosphatases. II
نویسندگان
چکیده
منابع مشابه
Angiotensin II-induced insulin resistance and protein tyrosine phosphatases.
Although the importance of protein tyrosine phosphorylation by tyrosine kinases in mitogenic signaling is well-accepted, recent studies also suggest that tyrosine dephosphorylation by protein tyrosine phosphatases (PTPases) play an equally important role. For example, both angiotensin II (Ang II) and insulin are known to mediate protein tyrosine phosphorylation and dephosphorylation events. The...
متن کاملStructure and mechanism of RNA polymerase II CTD phosphatases.
Recycling of RNA polymerase II (Pol II) after transcription requires dephosphorylation of the polymerase C-terminal domain (CTD) by the phosphatase Fcp1. We report the X-ray structure of the small CTD phosphatase Scp1, which is homologous to the Fcp1 catalytic domain. The structure shows a core fold and an active center similar to those of phosphotransferases and phosphohydrolases that solely s...
متن کاملBiochemical investigations on a transplantable rat leukemia. II. Liver phosphatases and glucose balance.
Glucose-6-phosphatase and fructose 1,6-diphosphatase activity per 100 gm. body weight was shown to be markedly increased in the liver cells of rats bearing two strains of leukemia (J and 302) when compared with normal animals. No differences in liver succinic acid dehydrogenase activity could be demonstrated between normal, J, and 302 leukemic animals. Leukemic animals failed to give an additio...
متن کاملRole of protein phosphatases in insulin-like growth factor II (IGF II)-stimulated mannose 6-phosphate/IGF II receptor redistribution.
The regulated expression of mannose 6-phosphate/insulin-like growth factor II (M6P/IGF II) receptors in plasma membranes has previously been shown to be accompanied by marked changes in the phosphorylation state of the receptors (Corvera, S., Folander, K., Clairmont, K. B., and Czech, M. P. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 7567-7571). In the present study we show that protein phosphat...
متن کاملThe Effect of Zinc on Alkaline Phosphatases”
Zinc has been shown to be an element essential to the life and growth of rats, but as yet there is no clear indication of what its function may be in metabolism. There are several reports of the occurrence of zinc in pure biological compounds. Scott and Fisher (1) have shown zinc to be necessary for the crystallization of insulin, although other metals were also effective. Keilin and Mann (2) r...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nippon kagaku zassi
سال: 1951
ISSN: 0369-5387,2185-0917
DOI: 10.1246/nikkashi1948.72.677